AI meets biotech? Ex-Meta scientists debut a giant AI protein design

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ESM3 is a frontier language model that can simultaneously reason about protein sequences, structures, and functions In tests, ESM3

Research Highlights · Simulating 500 million years of evolution with a language model · Engineering highly active and diverse nuclease enzymes by combining More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins

avent niplette Representative Publications: Simulating 500 million years of evolution with a language model Thomas Hayes*, Roshan Rao*, Halil Akin*, Nicholas J Sofroniew We can accelerate the timeline in a simulation and save having to wait a few million years to get results Hope I am not too far off… Upvote ·